Tuesday, July 21, 2020

Difference Between Vitiligo and Pityiriasis alba

Vitiligo

Vitiligo is an idiopathic disorder characterized by the disappearance of melanocytes in lesional skin resulting in sharply demarcated depigmented macules and patches ( get bigger with time ). Although often fairly distinct clinically, the differential diagnosis includes postinflammatory hypopigmentation, tinea versicolor, pityriasis alba, and, less commonly, hypopigmented mycosis fungoides (MF) and leprosy, among other entities. 

Vitiligo can appear in any age (usually starts at twenties) and any area of the body. About 15 to 25 percent of people with vitiligo are also affected by at least one other autoimmune disorder, such as Hashimoto's disease , Rheumatiod arthritis, Type 1 diabetes meliitus, psoriasis, Addison disease, or Systemic Lupus Erythematosus. In the absence of  autoimmune conditions, vitiligo does not affect general health or physical functioning.


Pityriasis Alba

Pityriasis alba (PA) is an eczematous dermatosis characterized by patchy hypopigmentation. It is usually seen in children, although it may occur in all skin types. It usually worsens during the summer, as the contrast between normal and lesional skin becomes greater with sun exposure. Lesions are usually asymptomatic, although they can be slightly pruritic.

Lesion reveals multiple, ill-defined, finely scaling patches that are symmetrically distributed. Lesions are most commonly found on the face (especially the cheeks). They may be slightly erythematous early on, then become hypopigmented. Lesions may persist for months to years, with a chronic relapsing course, but eventually resolve spontaneously without any medication.

Reference 

Soro, L. A. et al., 2013,'Inflammatory vitiligo versus hypopigmented mycosis fungoides in a 58-year-old Indian female', Indian Dermatol Online J, vol. 4, no. 4, pp. 321-325.

www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/pityriasis-alba/ (July 21, 2020, 20:21). 

No comments:

Post a Comment